Methanol Ultra LC-MS

TEST	U.M.	SPECIFICATION
Clearl colourless liquid appearance	-	Conform
Colour	Hazen	<= 10
Identification (IR)	-	Conform
Refractice index at 20°C	-	1.327 - 1.331
Water (KF)	mg/Kg	<= 200
Non volatile residue	mg/Kg	<= 2
Free alkali	meq/g	<= 0.00006
Assay (GC)	%	>= 99.95
UV transmittance	-	-
at 201 nm	%	>= 30
at 225 nm	%	>= 65
at 235 nm	%	>= 85
at 250 nm	%	>= 95
from 260 nm	%	>= 98
Fluorescence (quinine) at 254 nm	ppb	<= 1
Fluorescence (quinine) at 365 nm	ppb	<= 1
HPLC gradient test	-	Conform
(peak) at 235 nm	mAU	<= 2
(peak) at 254 nm	mAU	<= 1
Test LC-MS TIC (50-2000m/z) ESI (+)	-	-
Sensitive Impurities (reserpine)	ppb	<= 100
Aluminium (Al)	ppb	<= 50
Iron (Fe)	ppb	<= 50
Sodium (Na)	ppb	<= 50
Calcium (Ca)	ppb	<= 50
Magnesium (Mg)	ppb	<= 50
Potassium (K)	ppb	<= 50

Filtered through 0.1?m membrane. Binary gradient test conditions : water-methanol from 5 to 90% of methanol in 16 minutes at 1,8ml/min.